Ozempic and Wegovy both go under the skin, once a week, in the abdomen, thigh, or upper arm. This page quotes what each label actually says about that, explains why rotation keeps showing up in the instructions, and shows what is worth writing down afterward. (Ozempic PI; Wegovy PI)
It is not an injection-training substitute. The product Instructions for Use, the label for your specific medication, and your healthcare provider’s directions are the controlling sources.
What GLP-1 injection labels have in common
For Ozempic and Wegovy, the two once-weekly injectable semaglutide products on this page, the labels describe a subcutaneous injection, meaning the medicine is injected under the skin. The Ozempic label says to inject in the abdomen, thigh, or upper arm and to use a different injection site each week when injecting in the same body region. The Wegovy label also lists the abdomen, thigh, and upper arm, and says to rotate injection sites with each dose. Those are label facts, not a personalized recommendation for where you should inject. (Ozempic PI; Wegovy PI)
The same labels emphasize product-specific checks. Ozempic’s label says the medicine should look clear and colorless before use. Wegovy’s label gives the same kind of visual check for the injection solution. If anything about the medicine, pen, needle, or device looks different than the Instructions for Use describe, bring the question to a pharmacist or healthcare provider before using it. (Ozempic PI; Wegovy PI)
The administration steps the labels document
Dosley cannot train you to inject, and this page does not replace the Instructions for Use that ships with your product. What it can do is show what the Ozempic and Wegovy labels actually say about administration, in their own words, so you are not left guessing at the official source. (Ozempic PI; Wegovy PI)
Ozempic, section 2.1, Important Administration Instructions. Three of the section’s bullets are omitted here: concomitant insulin use, changing the weekly administration day, and the missed-dose instruction, which is quoted in full in the missed-dose guide. Read the whole section in the label. (Ozempic PI)
- Inspect OZEMPIC® visually before use. It should appear clear and colorless. Do not use OZEMPIC® if particulate matter and coloration is seen.
- Administer OZEMPIC® once weekly, on the same day each week, at any time of the day, with or without meals.
- Inject OZEMPIC® subcutaneously in the abdomen, thigh, or upper arm. Instruct patients to use a different injection site each week when injecting in the same body region.
— Ozempic (semaglutide) injection prescribing information, section 2.1, revised 05/2026 (Ozempic PI)
Wegovy, section 2.1, Important Monitoring and Administration Instructions. The section’s opening line (that WEGOVY® is administered in combination with a reduced-calorie diet and increased physical activity) is omitted here, as are the bullets on prescriber training, blood-glucose monitoring, and the tablet presentation. (Wegovy PI)
- Visually inspect the WEGOVY® injection prior to each administration. Only use if the solution is clear, colorless, and contains no particles.
- Administer WEGOVY® injection once weekly, on the same day each week, at any time of day, with or without meals.
- Inject WEGOVY® subcutaneously in the abdomen, thigh, or upper arm. The time of day and the injection site can be changed without the need for a dosage modification.
- Rotate injection sites with each dose.
— Wegovy prescribing information, section 2.1, revised 06/2026 (Wegovy PI)
Those are the labels’ words, not a Dosley recommendation about how you should inject. Note that they are written for a prescriber, and that they differ: Ozempic ties site rotation to the body region you are using, Wegovy ties it to every dose. Follow the label and Instructions for Use for the product you were actually prescribed. (Ozempic PI; Wegovy PI)
The three injection-site regions
The common question behind “how to inject GLP-1” is usually about body region. For Ozempic and Wegovy injections, the label-listed regions are:
- abdomen (Ozempic PI; Wegovy PI)
- thigh (Ozempic PI; Wegovy PI)
- upper arm (Ozempic PI; Wegovy PI)
That does not mean every region is equally practical for every person. Reach, visibility, mobility, skin changes, clothing, and whether a caregiver is helping can all affect what is workable. Dosley does not choose a site for you; it helps you keep a record of what happened after you followed the directions you were given.
For medication-specific pages, see the Dosley pages for Ozempic and Wegovy.
Rotation is part of the routine
Rotation is one of the simplest details to forget because weekly injections are spaced far apart. The Ozempic label says to use a different injection site each week when injecting in the same body region. The Wegovy label says to rotate injection sites with each dose. (Ozempic PI; Wegovy PI)
A tracker can make that less fuzzy. Instead of trying to remember where “last Monday” was, record the date, medication, body region, and any note your provider asked you to watch. Keep the note descriptive rather than diagnostic: for example, the body region used, whether the routine was on time, and any observation you want to discuss at the next appointment.
For a deeper rotation-focused checklist, read Injection site rotation: why and how.
What a label-based injection checklist can cover
A checklist is only as good as the source it points at. For Ozempic and Wegovy, that source is the label and the Instructions for Use:
- the medication and device named on your prescription
- the current Instructions for Use that shipped with that product
- the label’s own visual-inspection wording, quoted above
- the label’s own injection-region and rotation wording, quoted above
- date, medication, body region, and any observation to discuss later, which is the part Dosley keeps
This guide intentionally does not add dose changes, timing changes, or medical triage. Those are clinician decisions.
Missed-dose questions belong in the label
People searching injection guidance often also search what happens when a weekly routine slips. Missed a GLP-1 dose? What the official labels say reproduces the Ozempic and Wegovy missed-dose instructions verbatim, with attribution. The short version is not “Dosley says what to do”; it is “each label has its own missed-dose language, they do not agree with each other, and your provider or pharmacist can help apply the right one to your situation.” (Ozempic PI; Wegovy PI)
Pens and supply notes are arithmetic, not medical advice
Another practical injection question is how long a pen lasts. For Ozempic, the answer depends on the pen strength and prescribed dose. The official packaging table lists different dose counts for the initiation and maintenance pens. See How long does an Ozempic pen last? for the label-based arithmetic. (Ozempic PI)
Supply tracking is a planning record. It is not a reason to extend a device beyond instructions or alter medication use.
Storage is a separate handling question. See How to store GLP-1 medications correctly for label-cited storage notes and Traveling with GLP-1 pens for travel recordkeeping.
Ozempic and Wegovy share semaglutide, but the labels differ
Ozempic and Wegovy both contain semaglutide, but their current labels describe different approved uses and different product presentations. The practical takeaway is to avoid treating the brand names as interchangeable. For a label-only comparison, read Ozempic vs Wegovy: what’s actually different. (Ozempic PI; Wegovy PI)
What to track after an injection
Seven fields cover a weekly injection:
- date and time
- medication name
- dose as prescribed
- injection body region
- pen or device notes
- symptoms or observations you want to discuss
- weight or other wellness metrics you already track with your provider
Weekly dosing is the hard part to remember, because nothing happens for six days and then something does. A record you can scroll back through turns “I think it was a Tuesday” into a date you can read out at an appointment.
For the tracking system itself, see What to track during a GLP-1 routine.